Serum serial number 1.3
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Öztaş P, Önder M, Gönen S, Oztaş MÖ, Söylemezoğlu O. TNF-alpha inhibitors for chronic urticaria: Experience in 20 patients. Successful treatment of systemic cold contact urticaria with etanercept in a patient with psoriasis. Gualdi G, Monari P, Rossi M, Crotti S, Calzavara Pinton P. Journal of the American Academy of Dermatology. Treatment of refractory chronic urticaria with Tumor Necrosis Factor–alfa inhibitors. Wilson LH, Eliason MJ, Leiferman KM, Hull CM, Powell DL. Journal of Allergy and Clinical Immunology. Successful treatment of delayed pressure urticaria with anti–TNF-α. Magerl M, Philipp S, Manasterski M, Friedrich M, Maurer M. Increased levels of serum IL-31 in chronic spontaneous urticaria. Raap U, Wieczorek D, Gehring M, Pauls I, Ständer S, Kapp A, Wedi B. Increased circulating pro-inflammatory cytokines and imbalanced regulatory T-cell cytokines production in chronic idiopathic urticaria. ĭos Santos JC, Azor MH, Nojima VY, Lourenço FD, Prearo E, Maruta CW, et al. IL-6 transsignaling in patients with chronic spontaneous Urticaria. Kasperska Zajac A, Grzanka A, Damasiewicz Bodzek A.
SERUM SERIAL NUMBER 1.3 SKIN
Upregulation of TNF-α and IL-3 expression in lesional and uninvolved skin in different types of urticaria. Hermes B, Prochazka AK, Haas N, Jurgovsky K, Sticherling M, Henz BM. Study of serum Interleukin (IL) 18 and IL-6 levels in relation with the clinical disease severity in chronic idiopathic urticaria patients of Kashmir (North India). Rasool R, Ashiq I, Shera IA, Yousuf Q, Shah ZA. IL-6 as a keystone cytokine in health and disease.
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Autoreactive T cells in chronic spontaneous urticaria target the IgE Fc receptor Iα subunit. However, there was no significant difference between the patients with chronic urticaria and healthy controls in the serum levels of TNF-α (P=0.25), and IFN-ϒ (P=0.55), neither in the exact state nor by the Mann-Whitney U test.Ĭonclusion: Serum IL-6 level was elevated in patients with chronic urticaria, but the serum levels of IFN-ϒ and TNF-α were not significantly elevated.Īuyeung P, Mittag D, Hodgkin PD, Harrison LC. The serum IL-6 levels were elevated in the patients’ group (P=0.015). Results: The patients were divided into two groups comprising of 20 and 21 participants according to the results of Autologous Serum Skin Tests. Their serum IL-6, TNF-α, and IFN-ϒ levels were also evaluated. All patients underwent basic laboratory tests in addition to the Autologous Serum Skin Test. A questionnaire was filled and the disease activity score was determined in a one-week period for every patient. Materials and Methods: Forty-one patients with chronic urticaria referring to the Allergy Outpatient Clinic of Rasoul Akram Hospital and 20 healthy control subjects were enrolled in the study. This study evaluated the serum levels of Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF-α) and Interferon-ϒ (IFN-ϒ) in patients with chronic urticaria to find a biomarker. Background: The immunologic profile of chronic urticaria is not only important for diagnostic purposes, but also for therapeutic approaches.
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